| Main mode of Action Group
Primary Site of Action |
Chemical sub-group of Exemplifying Active Constituent | Active Constituents
|
| N-1
Acetylcholinesterase (AChE) inhibitors Nerve action |
N-1A
Carbamates |
Oxamyl (eg. Nemaguard®) |
| N-1B
Organophosphates |
Cadusafos (eg. Rugby®), Terbufos (eg. Counter®) | |
| N-2
Glutamate-gated Chloride (GluCl) channel allosteric modulators Nerve action |
N-2
Avermectins |
Abamectin (eg, Tervigo® Nematicide) |
| N-3
Mitochondrial complex II electron transport inhibitors. Succunate-coenzyme Q reductase MET II inhibitors |
N-3
Phenethyl pyridineamides Pyridinyl-ethyl-benzamides |
Cyclobutrifluram (Trefinti® Turf Nematicide, Vaniva® TymiriumTM Technology Nematicide)
Fluopyram (Indemnify® Turf Nematicide, Velum Prime® Nematicide) |
| N-UN
Compounds of unknown or uncertain MoA |
N-UN
imidazopyridine |
Fluazaindolizine (Salibro® Reklemel Active Nematicide) |
| N-UN
Heterocyclic fluoroalkenyl sulfone |
Fluensulfone (Nimtz® 180 EC Nematicide) | |
| N-UNX Unknown, multi-site |
N-UNX
Metham Sodium / Metham Potassium Various |
Metham
Dazomet (Basamid) |
| N-UNX
chloropicrin |
Chloropicrin (various) | |
| N-UNX
Halogenated hydrocarbon |
1,3-dichloropropene (Telone®) | |
| N-U*NX
Alkyl halides |
Methyl bromide (various)
Iodomethane (Mipic®) |
URL: https://croplife.org.au/resources/programs/resistance-management/nematicide-mode-of-action/
Content last updated: July 22, 2026
CropLife Australia’s Resistance Management Strategies provide a guide for crop protection product rotation through product groups. The strategies are a useful tool that supports farmers’ adoption of resistance management. All crop protection products must be handled and applied strictly as specified on the product label or APVMA permits.
These Resistance Management Strategies do not replace product labels. They are a guide only and do not endorse particular products, groups of products or cultural methods in terms of their performance. It is important to check with the Australian regulator’s (APVMA) product database for contemporary information on products and active constituents. The database can be sourced through www.apvma.gov.au
The information given in this strategy is provided in good faith and without any liability for loss or damage suffered as a result of its application and use. Advice given in this strategy is valid as at 22 July 2026. All previous versions of this strategy are now invalid.