Herbicide Mode of Action Table

Herbicide Mode of Action Groups

List of approved active constituents in each “Group” and, for ease of identification, the trade name of the first registered product or successor.  Refer to the APVMA website (www.apvma.gov.au) to obtain a complete list of registered products from the PUBCRIS database.

HIGH RESISTANCE RISK

Group 1

Inhibition of acetyl co-enzyme A carboxylase (ACC’ase inhibitors)

Chemical family Active constituent (first registered trade name)
Aryloxyphenoxy-propionates (FOPs) clodinafop (Topik®), cyhalofop (Agixa®*, Barnstorm®), diclofop (Cheetah® Gold* Decision®*, Hoegrass®), fenoxaprop (Cheetah®, Gold*, Wildcat®), fluazifop (Fusilade®, RoundupFNG Weedkiller®*), haloxyfop (Verdict®), propaquizafop (Shogun®), quizalofop (Targa®)
Cyclohexanediones (DIMs) butroxydim (Factor®*), clethodim (Select®, Zero Triple Action Garden Weedkiller®*), profoxydim (Aura®), sethoxydim (Cheetah® Gold*, Decision®*), tralkoxydim (Achieve®)
Phenylpyrazoles (DENs) pinoxaden (Axial®)

 

Group 2

Inhibition of acetolactate synthase (ALS inhibitors), acetohydroxyacid synthase (AHAS)

Chemical family Active constituent (first registered trade name)
Imidazolinones (IMIs) imazamox (Intervix®*, Raptor®), imazapic (Bobcat I-Maxx®*, Flame®, Midas®*, OnDuty®*), imazapyr (Arsenal Xpress®*, Intervix®*, Lightning®*, Midas®* OnDuty®*, Roundup PNG Weedkiller®*), imazethapyr (Lightning®*, Spinnaker®)
Pyrimidinyl–thio-benzoates bispyribac (Nominee®), pyrithiobac (Staple®)
Sulfonylureas (SUs) azimsulfuron (Gulliver®), bensulfuron (Londax®), chlorsulfuron (Glean®), ethoxysulfuron (Hero®), flazasulfuron (Katana®), foramsulfuron (Tribute®), halosulfuron (Sempra®), iodosulfuron (Hussar®), mesosulfuron (Atlantis®), metsulfuron (Ally®, , Stinger®*, Trounce®*, Ultimate Brushweed®* Herbicide), prosulfuron (Casper®*), rimsulfuron (Titus®), sulfometuron (Oust®, Eucmix Pre Plant®*, Trimac Plus®*), sulfosulfuron (Monza®), , triasulfuron (Logran®, Logran® B-Power®*), tribenuron (Express®), trifloxysulfuron (Envoke®, Krismat®*)
Triazolopyrimidines-Type 1 florasulam (Crest®*, Gangster®*, Paradigm®*, Vortex®*, X‑Pand®*), flumetsulam (Broadstrike®, Thistrol® Gold*), metosulam (Eclipse®)
Triazolopyrimidines-Type 2 pyroxsulam (Crusader® Rexade®*)

* This product contains more than one active constituent

MODERATE RESISTANCE RISK

Group 3

Inhibition of microtubule assembly

Chemical family Active constituent (first registered trade name)
Benzamides propyzamide (Effigy®*, Kerb®)
Benzoic acids chlorthal (Dacthal®, Prothal®*)
Dinitroanilines: (DNAs) oryzalin (Rout®*, Surflan®), pendimethalin (Freehand*®, OH2 Ornamental Herbicide®*, Stomp®), prodiamine (Barricade®), trifluralin (Bolta Duo®*, Jetti Duo®*, Treflan®)
Pyridines dithiopyr (Dimension®)

 

Group 4

Disruptors of plant cell growth (Auxin mimics)

Chemical family Active constituent (first registered trade name)
Benzoates dicamba (Banvel®, Banvel M®*, Barrel®*, Casper®*, Lawnweeder plus®*, Lawn weedkiller*, Mecoban®, Methar Tri-Kombi®*, Nuturf Millennium®*, Sandoban®*)
Phenoxy-carboxylates

(Phenoxys)

2,4-D (Actril DS®*, Amicide®, Fallow Boss Tordon®*, Methar Tri-Kombi®*, Pyresta®*, Vortex®*), 2,4-DB (Trifolamine®), dichlorprop (Lantana 600®), MCPA (Agtryne® MA*, Banvel M®*, Barrel®*, Basagran® M60*, Buctril® MA*, Buffalo Pro Weedkiller®*, Condor*®, Flight®*, Lawnweeder plus®*, Lawn Weedkiller*, Midas®*, Paragon®*, Precept®*, Quadrant®*, Silverado®*, Spearhead®*, Thistrol Gold*®, Tigrex®*, Tordon 242®*, Triathlon®*, Zero Triple Action Garden Weedkiller ®*), MCPB (Legumine®, Thistrol Gold*®), mecoprop  (Mecoban®, Mecopropamine®, Methar TriKombi®*, Multiweed®*)
Pyridine carboxylates

(Pyridines)

Aminocyclopyrachlor (Method®), aminopyralid (Fallow Boss Tordon®*, ForageMax®*, Grazon Extra®*, Grindstone®, Hotshot®*, Stinger®*, Vigilant II®*), clopyralid (Lontrel®, Nuturf Millennium®*, Spearhead®*, Trimac Plus®*, Velmac Plus®*) , florpyrauxifen (Agixa®*, Ubeniq®), halauxifen (ForageMax®*, Paradigm®*, Pixxaro®*, Rexade®*), picloram (Fallow Boss Tordon®*, Grazon Extra®*, Tordon®, Tordon 242®*, Tordon Regrowth Master®*, Trinoc®*, Vigilant II®*),
Quinoline-carboxylates quinclorac (Drive®)
Pyridyloxy-carboxylates fluroxypyr (Crest®*, Hotshot®*, Monsoon®*, Pixxaro®*,Roundup FNG Weedkiller®*, Roundup PNG Weedkiller®*,  Starane®), triclopyr (Garlon®, Grazon Extra®*, Tordon Regrowth Master®*, Tough Roundup® Weedkiller*, Ultimate Brushweed®* Herbicide)

Group 5

Inhibition of photosynthesis at photosystem II – D1 Serine 264 binders (and other non-histidine binders) (PS II Serine 264 inhibitors)

Chemical family Active constituent (first registered trade name)
Amides propanil (Stam®)
Phenylcarbamates phenmedipham (Betanal®)
Pyridazinones chloridazon (Pyramin®)
Triazines ametryn (Amigan®*, Gesapax® Combi*, Krismat®, Primatol Z®), atrazine (Gesapax® Combi*, Gesaprim®, Primextra® Gold*), cyanazine (Bladex®), prometryn (Bandit®*, Cotogard®*, Gesagard®), propazine (Agaprop®), simazine (Brunnings RTU Path Weeder®*, Gesatop®, Bantox®*, Yates Once A Year Path Weeder®*), terbuthylazine (Effigy*®, Firestorm®*, Palmero TX®*, Terbyne®), terbutryn (Agtryne® MA*, Amigan®*, Igran®)
Triazinones amicarbazone (Amitron®*) hexazinone (Bobcat I-Maxx®*, Velmac Plus®*, Velpar® K4*, Velpar® L), metribuzin (Aptitude®*, Sencor®)
Uracils bromacil (Hyvar®, Krovar®*), terbacil (Eucmix Pre Plant®*, Sinbar®, Trimac Plus®*)
Ureas diuron (Karmex®, Krovar®*, Velpar® K4*), fluometuron (Bandit®*, Cotogard®*, Cotoran®), linuron (Afalon®), metobromuron (Soleto®), methabenzthiazuron (Tribunil®), siduron (Tupersan®), tebuthiuron (Graslan®)

 

Group 6

Inhibition of photosynthesis at photosystem II – D1 Histadine 215 binders (PS II Histadine 215 inhibitors)

Chemical family Active constituent (first registered trade name)
Benzothiadiazinones bentazone (Basagran®, Basagran® M60*, Lawnweeder Plus®*)
Nitriles bromoxynil (Barrel®*, Buctril®, Buctril® MA*, Buffalo Pro Weedkiller®*, Eliminar C®*, Flight®*, Jaguar®*, Monsoon®*, Quadrant®*, Talinor®*, Triathlon®*, Velocity®*), ioxynil (Actril® DS*, Totril®)

 

 

Group 9

Inhibition of 5-enolpyruvyl shikimate-3 phosphate synthase (EPSP inhibition)

Chemical family Active constituent (first registered trade name)
Glycines glyphosate (Arsenal Xpress®*, Bantox*, Broadway®*, Firestorm®*, Illico®*, Resolva®*, Roundup®, Sandoban*®, Tough Roundup® Weedkiller*, Trounce®*,  Pathweeder®*)

 

Group 10

Inhibition of glutamine synthetase

Chemical family Active constituent (first registered trade name)
Phosphinic acids glufosinate (Basta®, Hellcat®*, Liberty®)

 

Group 12

Inhibition of carotenoid biosynthesis at the phytoene desaturase step (PDS inhibitors)

Chemical family Active constituent (first registered trade name)
N-Phenyl heterocycles norflurazon (Solicam®)
Phenyl-ethers diflufenican (Brodal®, Gangster®*, Infinity Ultra®*, Jaguar®*, Mateno® Complete*, Quadrant®*, Spearhead®*, Tigrex®*, Triathlon®*, Pathweeder®*), picolinafen (Eliminar C®*, Flight®*, Paragon®*, Quadrant®*, Sniper®)

 

Group 13

Inhibition of deoxy-D-xyulose phosphate synthase (DOXP inhibitors)

Chemical family Active constituent (first registered trade name)
Isoxazolidinones bixlozone (Overwatch®), clomazone (Altiplano®*, Command®)

 

 

Group 14

Inhibition of protoporphyrinogen oxidase (PPO inhibitors)

Chemical family Active constituent (first registered trade name)
Diphenyl ethers acifluorfen (Blazer®), fomesafen (Reflex®), oxyfluorfen (Goal®, OH2 Ornamental Herbicide®*, Rout®, Pathweeder®)
 N-Phenyl-oxadiazolones oxadiargyl (Raft®), oxadiazon (Ronstar®)
Phenylpyrazoles pyraflufen (Condor*®, Ecopar®, Pyresta®*)
N-Phenyl-imides butafenacil (B-Power®*, Logran® B-Power®*, Resolva®*), flumioxazin (Valor®, Terrain®), saflufenacil (Sharpen®, Voraxor*®), tiafenacil (Terrad’Or®), trifludimoxazin (Voraxor*®)
N-Phenyl-triazolinones carfentrazone (Affinity®, Aptitude®*, Broadway®, Buffalo Pro Weedkiller®*, Hellcat®*, Silverado®*)

 

Group 15

Inhibition of very long chain fatty acid synthesis (VLCFA inhibitors)

Chemical family Active constituent (first registered trade name)
α-Chloroacetamides dimethenamid (Freehand*, Frontier®-P, Outlook ®), metazachlor (Butisan®), metolachlor (Boxer® Gold*, Dual® Gold, Primextra® Gold*), propachlor (Prothal®*, Ramrod®)
Benzofurans ethofumesate (Tramat®)
Isoxazolines pyroxasulfone (Mateno® Complete*, Sakura®)
Thiocarbamates EPTC (Eptam®), molinate (Ordram®), pebulate (Tillam®), prosulfocarb (Arcade®, Bolta Duo®*, Boxer® Gold*, Diablo Duo®*), thiobencarb (Saturn®), tri-allate (Avadex®, Diablo Duo®*, Jetti Duo®*), vernolate (Vernam®)

 

Group 18

Inhibition of dihydropteroate synthase (DHP inhibitors)

Chemical family Active constituent (first registered trade name)
Carbamates asulam (Asulox®)

 

Group 19

Inhibition of auxin transport (ATIs)

Chemical family Active constituent (first registered trade name)
Aryl-carboxylates naptalam (Alanap-L®)

Group 22

Inhibition of photosynthesis at photosystem I via electron diversion (PSI electron diversion)

Chemical family Active constituent (first registered trade name)
Pyridiniums diquat (Reglone®, Spray Seed®*), paraquat (Alliance®*, Gramoxone®, Spray Seed®*)

 

Group 23

Inhibition of microtubule organisation

Chemical family Active constituent (first registered trade name)
Carbamates carbetamide (Carbetamex®, Ultro®), chlorpropham (Chlorpropham®)

 

Group 27

Inhibition of 4-hydroxyphenyl-pyruvate dioxygenase (HPPD inhibitors)

Chemical family Active constituent (first registered trade name)
Isoxazoles isoxaflutole (Balance® Palmero TX®*)
Pyrazoles benzofenap (Taipan®), pyrasulfotole (Galaxy®, Infinity Ultra®*, Precept®*, Velocity®*) topramezone (Frequency®)
Triketones bicyclopyrone (Talinor®*), mesotrione (Callisto®)

 

Group 29

Inhibition of cellulose biosynthesis

Chemical family Active constituent (first registered trade name)
Alkylazines indaziflam (Specticle®)
Benzamides isoxaben (Gallery®, X-Pand®*)
Nitriles dichlobenil (Casoron®)

 

Group 30

Inhibition of fatty acid thioesterase

Chemical family Active constituent (first registered trade name)
Benzyl ether cinmethylin (Luximax®), methiozolin (PoaCure Turf®)

 

 

Group 31

Inhibition of serine-threonine protein phosphatase (STPP inhibitors)

Chemical family Active constituent (first registered trade name)
Unknown endothal (Endothal®)

 

Group 32

Inhibition of solanesyl diphosphate synthase

Chemical family Active constituent (first registered trade name)
Diphenyl ether aclonifen (Mateno® Complete*)

 

Group 34

Inhibition of lycopene cyclase

Chemical family Active constituent (first registered trade name)
Triazoles amitrole (Alliance®*, Amitrole®, RTU Pathweeder®*, Illico®*, Firestorm®*, Onceyear Pathweeder®*)

 

Group 0

Herbicides with unknown mode of action

Chemical family Active constituent (first registered trade name)
Arylaminopropionic acids flamprop (Mataven® L)
Acetamides napropamide (Altiplano®*, Devrinol®)
Organoarsenicals DSMA (disodium methylarsonate) (Methar®, Trinoc®*), MSMA (monosodium methylarsonate) (Daconate®)
Fatty acids Pelargonic acid (Nonanoic acid) Roundup FNG Weedkiller®*, Roundup PNG Weedkiller®*, Slasher®, Zero Triple Action Garden Weedkiller®*)
Chlorocarbonic acids dalapon (Dalapon®, Onceyear Pathweeder®*, flupropanate (Frenock®)
Phosphorodithioates bensulide (Prefar®)

* This product contains more than one active constituent

 

 

NOTES

  1. List of approved active constituents in each “Group” and, for ease of identification, at the discretion of the Expert Committee on Herbicide Resistance.
  2. the trade name of the first registered product or successor.
  3. Refer to the APVMA website (apvma.gov.au) to obtain a complete list of registered products from the PUBCRIS database.

 


URL: https://croplife.org.au/resources/programs/resistance-management/herbicide-moa-table-4/
Content last updated: June 26, 2024

CropLife Australia’s Resistance Management Strategies provide a guide for crop protection product rotation through product groups. The strategies are a useful tool that supports farmers’ adoption of resistance management. All crop protection products must be handled and applied strictly as specified on the product label or APVMA permits.

These Resistance Management Strategies do not replace product labels. They are a guide only and do not endorse particular products, groups of products or cultural methods in terms of their performance. It is important to check with the Australian regulator’s (APVMA) product database for contemporary information on products and active constituents. The database can be sourced through www.apvma.gov.au

The information given in this strategy is provided in good faith and without any liability for loss or damage suffered as a result of its application and use. Advice given in this strategy is valid as at 26 June 2024. All previous versions of this strategy are now invalid.