High resistance risk
Group 1
Inhibition of acetyl co-enzyme A carboxylase (ACC’ase inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Aryloxyphenoxy-propionates (FOPs) | clodinafop (Topik®), cyhalofop (Agixa®*, Barnstorm®), diclofop (Cheetah® Gold* Decision®*, Hoegrass®), fenoxaprop (Cheetah®, Gold*, Wildcat®), fluazifop (Fusilade®, RoundupFNG Weedkiller®*), haloxyfop (Verdict®), propaquizafop (Shogun®), quizalofop (Targa®) |
| Cyclohexanediones (DIMs) | butroxydim (Factor®*), clethodim (Select®, Zero Triple Action Garden Weedkiller®*), profoxydim (Aura®), sethoxydim (Cheetah® Gold*, Decision®*), tralkoxydim (Achieve®) |
| Phenylpyrazoles (DENs) | pinoxaden (Axial®) |
Group 2
Inhibition of acetolactate synthase (ALS inhibitors), acetohydroxyacid synthase (AHAS)
| Chemical family | Active constituent (first registered trade name) |
| Imidazolinones (IMIs) | imazamox (Intervix®*, Raptor®), imazapic (Bobcat I-Maxx®*, Flame®, Midas®*, OnDuty®*), imazapyr (Arsenal Xpress®*, Intervix®*, Lightning®*, Midas®* OnDuty®*, Roundup PNG Weedkiller®*), imazethapyr (Lightning®*, Spinnaker®) |
| Pyrimidinyl–thio-benzoates | bispyribac (Nominee®), pyrithiobac (Staple®) |
| Sulfonylureas (SUs) | azimsulfuron (Gulliver®), bensulfuron (Londax®), chlorsulfuron (Glean®), ethoxysulfuron (Hero®), flazasulfuron (Katana®), foramsulfuron (Tribute®), halosulfuron (Sempra®), iodosulfuron (Hussar®), mesosulfuron (Atlantis®), metsulfuron (Ally®, , Stinger®*, Trounce®*, Ultimate Brushweed®* Herbicide), prosulfuron (Casper®*), rimsulfuron (Titus®), sulfometuron (Oust®, Eucmix Pre Plant®*, Trimac Plus®*), sulfosulfuron (Monza®), , triasulfuron (Logran®, Logran® B-Power®*), tribenuron (Express®), trifloxysulfuron (Envoke®, Krismat®*) |
| Triazolopyrimidines-Type 1 | florasulam (Crest®*, Gangster®*, Paradigm®*, Vortex®*, X‑Pand®*), flumetsulam (Broadstrike®, Thistrol® Gold*), metosulam (Eclipse®) |
| Triazolopyrimidines-Type 2 | pyroxsulam (Crusader® Rexade®*) |
* This product contains more than one active constituent.
Moderate resistance risk
Group 3
Inhibition of microtubule assembly – α-tubulin
| Chemical family | Active constituent (first registered trade name) |
| Dinitroanilines: (DNAs) | oryzalin (Rout®*, Surflan®), pendimethalin (Freehand*®, OH2 Ornamental Herbicide®*, Stomp®), prodiamine (Barricade®), trifluralin (Bolta Duo®*, Jetti Duo®*, Treflan®) |
| Pyridines | dithiopyr (Dimension®) |
Group 4
Disruptors of plant cell growth (Auxin mimics)
| Chemical family | Active constituent (first registered trade name) |
| Benzoates | dicamba (Banvel®, Banvel M®*, Barrel®*, Casper®*, Lawnweeder plus®*, Lawn weedkiller*, Mecoban®, Methar Tri-Kombi®*, Nuturf Millennium®*, Sandoban®*) |
| Phenoxy-carboxylates
(Phenoxys) |
2,4-D (Actril DS®*, Amicide®, Fallow Boss Tordon®*, Methar Tri-Kombi®*, Pyresta®*, Vortex®*), 2,4-DB (Trifolamine®), dichlorprop (Lantana 600®), MCPA (Agtryne® MA*, Banvel M®*, Barrel®*, Basagran® M60*, Buctril® MA*, Buffalo Pro Weedkiller®*, Condor*®, Flight®*, Lawnweeder plus®*, Lawn Weedkiller*, Midas®*, Paragon®*, Precept®*, Quadrant®*, Silverado®*, Spearhead®*, Thistrol Gold*®, Tigrex®*, Tordon 242®*, Triathlon®*, Zero Triple Action Garden Weedkiller ®*), MCPB (Legumine®, Thistrol Gold*®), mecoprop (Mecoban®, Mecopropamine®, Methar TriKombi®*, Multiweed®*) |
| Pyridine carboxylates
(Pyridines) |
Aminocyclopyrachlor (Method®), aminopyralid (Fallow Boss Tordon®*, ForageMax®*, Grazon Extra®*, Grindstone®, Hotshot®*, Stinger®*, Vigilant II®*), clopyralid (Lontrel®, Nuturf Millennium®*, Spearhead®*, Trimac Plus®*, Velmac Plus®*) , florpyrauxifen (Agixa®*, Ubeniq®), halauxifen (ForageMax®*, Paradigm®*, Pixxaro®*, Rexade®*), picloram (Fallow Boss Tordon®*, Grazon Extra®*, Tordon®, Tordon 242®*, Tordon Regrowth Master®*, Trinoc®*, Vigilant II®*), |
| Quinoline-carboxylates | quinclorac (Drive®) |
| Pyridyloxy-carboxylates | fluroxypyr (Crest®*, Hotshot®*, Monsoon®*, Pixxaro®*,Roundup FNG Weedkiller®*, Roundup PNG Weedkiller®*, Starane®), triclopyr (Garlon®, Grazon Extra®*, Tordon Regrowth Master®*, Tough Roundup® Weedkiller*, Ultimate Brushweed®* Herbicide) |
Group 5
Inhibition of photosynthesis at photosystem II – D1 Serine 264 binders (and other non-histidine binders) (PS II Serine 264 inhibitors )
| Chemical family | Active constituent (first registered trade name) |
| Amides | propanil (Stam®) |
| Phenylcarbamates | phenmedipham (Betanal®) |
| Pyridazinones | chloridazon (Pyramin®) |
| Triazines | ametryn (Amigan®*, Gesapax® Combi*, Krismat®, Primatol Z®), atrazine (Gesapax® Combi*, Gesaprim®, Primextra® Gold*), cyanazine (Bladex®), prometryn (Bandit®*, Cotogard®*, Gesagard®), propazine (Agaprop®), simazine (Brunnings RTU Path Weeder®*, Gesatop®, Bantox®*, Yates Once A Year Path Weeder®*), terbuthylazine (Effigy*®, Firestorm®*, Palmero TX®*, Terbyne®), terbutryn (Agtryne® MA*, Amigan®*, Igran®) |
| Triazinones | amicarbazone (Amitron®*) hexazinone (Bobcat I-Maxx®*, Velmac Plus®*, Velpar® K4*, Velpar® L), metribuzin (Aptitude®*, Sencor®) |
| Uracils | bromacil (Hyvar®, Krovar®*), terbacil (Eucmix Pre Plant®*, Sinbar®, Trimac Plus®*) |
| Ureas | diuron (Karmex®, Krovar®*, Velpar® K4*), fluometuron (Bandit®*, Cotogard®*, Cotoran®), linuron (Afalon®), metobromuron (Soleto®), methabenzthiazuron (Tribunil®), siduron (Tupersan®), tebuthiuron (Graslan®) |
Group 6
Inhibition of photosynthesis at photosystem II – D1 Histadine 215 binders (PS II Histadine 215 inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Benzothiadiazinones | bentazone (Basagran®, Basagran® M60*, Lawnweeder Plus®*) |
| Nitriles | bromoxynil (Barrel®*, Buctril®, Buctril® MA*, Buffalo Pro Weedkiller®*, Eliminar C®*, Flight®*, Jaguar®*, Monsoon®*, Quadrant®*, Talinor®*, Triathlon®*, Velocity®*), ioxynil (Actril® DS*, Totril®) |
Group 9
Inhibition of 5-enolpyruvyl shikimate-3 phosphate synthase (EPSP inhibition)
| Chemical family | Active constituent (first registered trade name) |
| Glycines | glyphosate (Arsenal Xpress®*, Bantox*, Broadway®*, Firestorm®*, Illico®*, Resolva®*, Roundup®, Sandoban*®, Tough Roundup® Weedkiller*, Trounce®*, Pathweeder®*) |
Group 10
Inhibition of glutamine synthetase
| Chemical family | Active constituent (first registered trade name) |
| Phosphinic acids | glufosinate-ammonium (Basta®, Hellcat®*, Liberty®), glufosinate-p-ammonium (Basta® Ultra, Liberty® Ultra) |
Group 12
Inhibition of carotenoid biosynthesis at the phytoene desaturase step (PDS inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| N-Phenyl heterocycles | norflurazon (Solicam®) |
| Phenyl-ethers | diflufenican (Brodal®, Gangster®*, Infinity Ultra®*, Jaguar®*, Mateno® Complete*, Quadrant®*, Spearhead®*, Tigrex®*, Triathlon®*, Pathweeder®*), picolinafen (Eliminar C®*, Flight®*, Paragon®*, Quadrant®*, Sniper®) |
Group 13
Inhibition of deoxy-D-xyulose phosphate synthase (DOXP inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Isoxazolidinones | bixlozone (Overwatch®), clomazone (Altiplano®*, Command®) |
Group 14
Inhibition of protoporphyrinogen oxidase (PPO inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Diphenyl ethers | acifluorfen (Blazer®), fomesafen (Reflex®), oxyfluorfen (Goal®, OH2 Ornamental Herbicide®*, Rout®, Pathweeder®) |
| N-Phenyl-oxadiazolones | oxadiargyl (Raft®), oxadiazon (Ronstar®) |
| Phenylpyrazoles | pyraflufen (Condor*®, Ecopar®, Pyresta®*) |
| N-Phenyl-imides | butafenacil (B-Power®*, Logran® B-Power®*, Resolva®*), flumioxazin (Valor®, Terrain®), saflufenacil (Sharpen®, Voraxor*®), tiafenacil (Terrad’Or®), trifludimoxazin (Voraxor*®) |
| N-Phenyl-triazolinones | carfentrazone (Affinity®, Aptitude®*, Broadway®, Buffalo Pro Weedkiller®*, Hellcat®*, Silverado®*) |
Group 15
Inhibition of very long chain fatty acid synthesis (VLCFA inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| α-Chloroacetamides | dimethenamid-p(Freehand*, Frontier®-P, Outlook ®), metazachlor (Butisan®), metolachlor (Boxer® Gold*, Dual® Gold, Primextra® Gold*), propachlor (Prothal®*, Ramrod®) |
| Benzofurans | ethofumesate (Tramat®) |
| Isoxazolines | pyroxasulfone (Mateno® Complete*, Sakura®) |
| Thiocarbamates | EPTC (Eptam®), molinate (Ordram®), pebulate (Tillam®), prosulfocarb (Arcade®, Bolta Duo®*, Boxer® Gold*, Diablo Duo®*), thiobencarb (Saturn®), tri-allate (Avadex®, Diablo Duo®*, Jetti Duo®*), vernolate (Vernam®) |
Group 18
Inhibition of dihydropteroate synthase (DHP inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Carbamates | asulam (Asulox®) |
Group 19
Inhibition of auxin transport (ATIs)
| Chemical family | Active constituent (first registered trade name) |
| Aryl-carboxylates | naptalam (Alanap-L®) |
Group 22
Inhibition of photosynthesis at photosystem I via electron diversion (PSI electron diversion)
| Chemical family | Active constituent (first registered trade name) |
| Pyridiniums | diquat (Reglone®, Spray Seed®*), paraquat (Alliance®*, Gramoxone®, Spray Seed®*) |
Group 23
Microtubule interference – unclear site of action
| Chemical family | Active constituent (first registered trade name) |
| Benzamides | propyzamide (Effigy®*, Kerb®) |
| Carbamates | carbetamide (Carbetamex®, Ultro®), chlorpropham (Chlorpropham®) |
Group 27
Inhibition of 4-hydroxyphenyl-pyruvate dioxygenase (HPPD inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Isoxazoles | isoxaflutole (Balance® Palmero TX®*) |
| Pyrazoles | benzofenap (Taipan®), pyrasulfotole (Galaxy®, Infinity Ultra®*, Precept®*, Velocity®*), topramezone (Frequency®) |
| Triketones | bicyclopyrone (Talinor®*), mesotrione (Callisto®) |
Group 29
Inhibition of cellulose biosynthesis
| Chemical family | Active constituent (first registered trade name) |
| Alkylazines | indaziflam (Specticle®) |
| Benzamides | isoxaben (Gallery®, X-Pand®*) |
| Nitriles | dichlobenil (Casoron®) |
Group 30
Inhibition of fatty acid thioesterase
| Chemical family | Active constituent (first registered trade name) |
| Benzyl ether | cinmethylin (Luximax®), methiozolin (PoaCure Turf®) |
Group 31
Inhibition of serine-threonine protein phosphatase (STPP inhibitors)
| Chemical family | Active constituent (first registered trade name) |
| Unknown | endothal (Endothal®) |
Group 32
Inhibition of solanesyl diphosphate synthase
| Chemical family | Active constituent (first registered trade name) |
| Diphenyl ether | aclonifen (Mateno® Complete*) |
Group 34
Inhibition of lycopene cyclase
| Chemical family | Active constituent (first registered trade name) |
| Triazoles | amitrole (Alliance®*, Amitrole®, RTU Pathweeder®*, Illico®*, Firestorm®*, Onceyear Pathweeder®*) |
Group 0
Herbicides with unknown mode of action
| Chemical family | Active constituent (first registered trade name) |
| Arylaminopropionic acids | flamprop (Mataven® L) |
| Acetamides | napropamide (Altiplano®*, Devrinol®) |
| Organoarsenicals | DSMA (disodium methylarsonate) (Methar®, Trinoc®*), MSMA (monosodium methylarsonate) (Daconate®) |
| Fatty acids | Pelargonic acid (Nonanoic acid) Roundup FNG Weedkiller®*, Roundup PNG Weedkiller®*, Slasher®, Zero Triple Action Garden Weedkiller®*) |
| Chlorocarbonic acids | dalapon (Dalapon®, Onceyear Pathweeder®*, flupropanate (Frenock®) |
| Phosphorodithioates | bensulide (Prefar®) |
* This product contains more than one active constituent
Notes
URL: https://croplife.org.au/resources/programs/resistance-management/herbicide-moa-table-4/
Content last updated: July 22, 2026
CropLife Australia’s Resistance Management Strategies provide a guide for crop protection product rotation through product groups. The strategies are a useful tool that supports farmers’ adoption of resistance management. All crop protection products must be handled and applied strictly as specified on the product label or APVMA permits.
These Resistance Management Strategies do not replace product labels. They are a guide only and do not endorse particular products, groups of products or cultural methods in terms of their performance. It is important to check with the Australian regulator’s (APVMA) product database for contemporary information on products and active constituents. The database can be sourced through www.apvma.gov.au
The information given in this strategy is provided in good faith and without any liability for loss or damage suffered as a result of its application and use. Advice given in this strategy is valid as at 22 July 2026. All previous versions of this strategy are now invalid.